The Ackermann Group
Catalysis And Organic Synthesis

Flow Chemistry

The use of continuous flow methods in CH activation catalysis is an important process for scaling-up and is particularly suited for for heterogeneous catalysis, with beneficial consequences such as the possibility to reduce the amount of solvent and the increased mechanical stability of the catalyst.

Selected publications:

H. Wang,' F. Pesciaioli,' J. C. A. Oliveira, S. Warratz, L. Ackermann, "Synergistic Manganese(I) CH Activation Catalysis in Continuous Flow: Chemo-Selective Hydroarylation" Angew. Chem. Int. Ed. 2017, 56, 1506315067.

F. Ferlin, S. Santoro, L. Ackermann, L. Vaccaro, "Heterogeneous CH Alkenylations in Continuous-Flow: Oxidative Palladium-Catalysis in a Biomass-Derived Reaction Medium" Green Chem. 2017, 19, 25102514.