The Ackermann Group
Catalysis And Organic Synthesis

List of Publications




2019

352) C. Zhu, M. Stangier, J. C. A. Oliveira, L. Massignan, L. Ackermann, "Iron-Electro-Catalyzed C–H Arylations: Mechanistic Insights Into Oxidation-Induced Reductive Elimination through Spectroscopy, CV, and Computation for Ferraelectrocatalysis" Chem. Eur. J. 2019, 25, in press. Abstract>

351) E. Gońka,’ L. Yang,’ R. Steinbock, F. Pescaioli, R. Kuniyil, L. Ackermann, "π-Extended Polyaromatic Hydrocarbons by Sustainable Alkyne Annulations through Double C–H/N–H Activation" Chem. Eur. J. 2019, 25, in press. ' These authors contributed equally. Abstract>

350) V. Müller, R. Weck, V. Derdau, L. Ackermann, "Ruthenium(II)-Catalyzed Hydrogen Isotope Exchange of Pharmaceutical Drugs by C–H Deuteration and C–H Tritiation" ChemCatChem 2019, 11, in press. Abstract>

349) W.-J. Kong, L. H. Finger, A. M. Messinis, R. Kuniyil, J. C. A. Oliveira, L. Ackermann, "Flow Rhodaelectro-Catalyzed Alkyne Annulations by Versatile C−H Activation: Mechanistic Support for Rhodium(III/IV)" J. Am. Chem. Soc. 2019, 141, 17198-17206. Abstract>

348) L. Capdevila, T. H. Meyer, S. Roldán-Gómez, J. M. Luis, Lutz Ackermann, X. Ribas, "Chemo-Divergent Nickel(0)-Catalyzed Arene C–F Activation with Alkynes: Unprecedented C-F/C-H Double-Insertion" ACS Catal. 2019, 9, 11074-11081. Abstract>

347) T. Rogge, L. Ackermann, "Arene-Free Ruthenium(II/IV)-Catalyzed Bifurcated Arylation for Oxidative C–H/C–H Functionalizations" Angew. Chem. Int. Ed. 2019, 58, 15640-15645. Abstract>

346) J. Jiang, H. Liu, L. Cao, C. Zhao, Y. Liu, L. Ackermann, Z. Ke, "Metallalkenyl, Metallacyclopropene, or Metallallylcarbenoid? Ru-Catalyzed Annulation between Benzoic Acid and Alkyne" ACS Catal. 2019, 9, 9387-9392. Abstract>

345) S. Chen, W. Chen, X. Chen, G. Chen, L. Ackermann, X. Tian, "Copper(I)-Catalyzed Oxyamination of β,γ-Unsaturated Hydrazones: Synthesis of Dihydropyrazoles" Org. Lett. 2019, 21, 7787-7790. Abstract>

344) F. Ferlin, A. Marini, N. Ascani, L. Ackermann, D. Lanari, L. Vaccaro, "Heterogeneous Manganese-Catalyzed Oxidase C–H/C–O Cyclization to Access Pharmaceutically Active Compounds" ChemCatChem 2019, 11, in press. Abstract>

343) J. A. Ellman, L. Ackermann, B.-F. Shi, "The Breadth and Depth of C-​H Functionalization" J. Org. Chem. 2019, 84, 12701-12704. Abstract>

342) M. Virelli,' W. Wang,' R. Kuniyil, J. Wu, G. Zanoni, A. Fernandez, J. Scott, M Vendrel, L. Ackermann, "BODIPY-Labeled Cyclobutanes by Secondary C(sp3)─H Arylations for Live-Cell Imaging" Chem. Eur. J. 2019, 25, 12712-12718. ' These authors contributed Abstract>

341) A. Çapcı, M. M. Lorion, H. Wang, N. Simon,  M. Leidenberger, M. C. Borges Silva, D. R. M. Moreira, Z. Yongping, M. Yuqing, C. J. Yun, Y. M. Lee, O. Friedrich,  B. Kappes, J. Wang, L. Ackermann, S. B. Tsogoeva, "Artemisinin‐(Iso)Quinoline Hybrids by C‐H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria" Angew. Chem. Int. Ed. 2019, 58, 13066-13079. Abstract> (highlighted in Nature)

340) T. E. Boddie, S. H. Carpenter, T. M. Baker, J. C. DeMuth, G. Cera, W. W. Brennessel, L. Ackermann, M. L. Neidig, "Identification and Reactivity of Cyclometalated Iron(II) Intermediates in Triazole-Directed Iron-Catalyzed C-H Activation" J. Am. Chem. Soc. 2019, 141, 12338-12345. Abstract>

339) C. Tian, U. Dhawa, A. Scheremetjew, L. Ackermann, "Cupraelectro-Catalyzed Alkyne Annulation: Evidence for Distinct C–H Alkynylation and Decarboxylative C–H/C–C Manifolds" ACS Catal. 2019, 9, 7690-7696. Abstract>

338) A. Schischko,' N. Kaplaneris,' T. Rogge, G. Sirvinskaite, J. Son, L. Ackermann, "Late-stage peptide C–H alkylation for bioorthogonal C–H activation featuring solid phase peptide synthesis" Nature Commun. 2019, 10, 3553. ' These authors contributed equally. Abstract>

337) R. Mei, W. Ma, Y. Zhang, X. Guo, L. Ackermann, "Cobaltaelectro-Catalyzed Oxidative C−H/N−H Activation with 1,3-diynes by Electro-Removable Hydrazides" Org. Lett. 2019, 21, 6534-6538. Abstract>

336) F. Ferlin, S. R. Yetra, Svenja Warratz, L. Vaccaro, L. Ackermann, "Reusable Pd@PEG Catalyst for Aerobic Dehydrogenative C–H/C–H Arylations of 1,2,3-Triazoles" Chem. Eur. J. 2019, 25, 11427-11431. Abstract>

335) W. Wang,' P. Subramanian,' O. Martinazzoli, J. Wu, L. Ackermann, "Glycopeptides by Linch-Pin C–H Activations for Peptide-Carbohydrate Conjugation by Manganese(I)-Catalysis" Chem. Eur. J. 2019, 25, 10585-10589. ' These authors contributed equally. Abstract>

334) J. Mo,' T. Müller,' J. C. A. Oliveira,' S. Demeshko, F. Meyer, L. Ackermann, "Iron‐Catalyzed C–H Activation with Propargyl Acetates: Mechanistic Insights on Iron(II) by Experiment, Kinetics, Mössbauer Spectroscopy and Computation" Angew. Chem. Int. Ed. 2019, 58, 13006-13010. ' These authors contributed equally. Abstract>

333) E. N. da Silva Júnior, G. A. M. Jardim, C. Jacob, U. Dhawa, L. Ackermann, S. L. de Castro, "Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones" Eur. J. Med. Chem. 2019, 179, 863-915. Abstract>

332) P. Gandeepan, J. Koeller, K. Korvorapun, J. Mohr, L. Ackermann, "Visible-Light for Ruthenium-Catalyzed meta-C‒H Alkylation at Room Temperature" Angew. Chem. Int. Ed. 2019, 58, 9820-9825. Abstract>

331) J. Loup, U. Dhawa, F. Pesciaioli, J. Wencel-Delord, L. Ackermann, "Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals" Angew. Chem. Int. Ed. 2019, 58, 12803-12818. Abstract>

330) T. H. Meyer, L. H. Finger, P. Gandeepan, L. Ackermann, "Resource Economy by Metallaelectrocatalysis: Merging Electrochemistry and C–H Activation" Trends Chem. 2019, 1, 63-76. Abstract>

329) W.-J. Kong, L. H. Finger, J. C. A. Oliveira, L. Ackermann, "Rhodaelectrocatalysis for Annulative C–H Activation: Polycyclic Aromatic Hydrocarbons by Versatile Double Electrocatalysis" Angew. Chem. Int. Ed. 2019, 58, 6342-6346. Abstract>

328) Y. Qiu, J. Struwe, L. Ackermann, "Metallaelectro-Catalyzed C–H Activation by Weak Coordination" Synlett 2019, 30, 1164-1173. Abstract>

327) S. Chandra Sau, R. Mei, J. Struwe, L. Ackermann, "Cobaltaelectro-Catalyzed C–H Activation with Carbon Monoxide or Isocyanides" ChemSusChem 2019, 12, 3023-3027. Abstract>

326) S. Han, S. Liu, L. Liu, L. Ackermann, J. Li, "Cobalt-Catalyzed Diastereoselective Difluoroalkylation/Giese Addition Domino Reactions" Org. Lett. 2019, 21, 5387-5391. Abstract>

325) G. Parthasarathy, N. Kaplaneris, S. Santoro, L. Vaccaro, L. Ackermann, "Biomass-Derived Solvents for Sustainable Transition Metal-Catalyzed C-H Activation" ACS Sustain. Chem. Eng. 2019, 7, 8023-8040. Abstract>

324) J. Loup, T. Parchomyk, S. Lülf, S. Demeshko, F. Meyer, K. Koszinowski, L. Ackermann, "Mössbauer and mass spectrometry support for iron(II) catalysts in enantioselective C–H activation" Dalton Trans. 2019, 48, 5135-5139. Abstract>

323) H. Long, K. Xu, S. Chen, J. Lin, D. Wu, B. Wu, X. Tian, L. Ackermann, "Nickel-Catalyzed Intramolecular Direct Arylation of Imines towards Diverse Indoles" Org. Lett. 2019, 21, 3053-3056. Abstract>

322) S. Santoro, F.Ferlin, L. Ackermann, L. Vaccaro, "C–H Functionalization Reactions in Flow Conditions" Chem. Soc. Rev. 2019, 48, 2767-2782. Abstract>

321) S. R. Yetra, T. Rogge, S. Warratz, J. Struwe, W. Peng, P. Vana, L. Ackermann, "Micellar Catalysis for Ruthenium(II)-Catalyzed C−H Arylation: Weak-Coordination-Enabled C−H Activation in H2O" Angew. Chem. Int. Ed. 2019, 58, 7490-7494. Abstract>

320) P. Gandeepan, T. Müller, D. Zell, G. Cera, S. Warratz, L. Ackermann, "3d Transition Metals for C–H Activation" Chem. Rev. 2019, 119, 2192-2452. Abstract>

319) P. Chen, Y. Hao, X. Wang, D. Yuan, Y. Yao, L. Ackermann, "Directing Group-free C7-alkylations of N-alkylindols Mediated by Cationic Zirconium Complexes: Role of Brønsted Acid for Catalytic Manifold" Chem. Eur. J. 2019, 25, 7292-7297. Abstract>

318) P. Gandeepan, L. Ackermann, "Diastereoselective Formation of Alkenes through C(sp2)–H Bond Activation", in CH-Activation for Asymmetric Synthesis (Eds.: F. Colobert, J. Wence-Delord), Wiley-VCH, Weinheim, 2019, 239-281. Abstract>

317) C. Tian, U. Dhawa, J. Struwe, L. Ackermann, "Cobaltaelectro-Catalyzed C–H Acyloxylation" Chin. J. Chem. 2019, 37, 552-556. Abstract>

316) C. Zhu, R. Kuniyil, L. Ackermann, "Manganese(I)-Catalyzed C–H Activation/Diels-Alder/retro-Diels-Alder Domino Alkyne Annulation by Transformable Pyridines" Angew. Chem. Int. Ed. 2019, 58, 5338-5342. Abstract>

315) Z. Ruan, Z. Huang, Z. Xu, G. Mo, X. Tian,X.-Y. Yu, L. Ackermann, "Catalyst-Free, Direct Electrochemical Tri- and Difluoroalkylation/Cyclization: Access to Functionalized Oxindoles and Quinolinones" Org. Lett. 2019, 21, 1237-1240. Abstract>

314) Y. Qiu,' A. Scheremetjew', L. Ackermann, "Electrooxidative C–C Alkenylation by Rhodium(III) Catalysis" J. Am. Chem. Soc. 2019, 141, 2731-2738. ' Both authors contributed equally. Abstract>

313) Z. Shen, H. Huang, C. Zhu, S. Warratz, L. Ackermann, "MnCl2-Catalyzed C–H Alkylation on Azine Heterocycles" Org. Lett. 2019, 21, 571-574. Abstract>

312) D Ghorai, J. Loup, G. Zanoni, L. Ackermann, "Air-Stable Secondary Phosphine Oxides (SPOs) for Nickel-Catalyzed Cross-Couplings of Aryl Ethers by C–O Activation" Synlett 2019, 30, 429-432. Abstract>

311) G. G. Dias, T. A. do Nascimento, A. K. A. de Almeida, A. C. S. Bombaça, R. F. S. Menna-Barreto, C. Jacob, S. Warratz, E. N. da Silva Júnior, L. Ackermann, "Ruthenium(II)-Catalyzed C–H Alkenylation of Quinones: Diversity-Oriented Strategy for Trypanocidal Compounds" Eur. J. Org. Chem. 2019, 2344-2353. Abstract>

310) N. Kaplaneris, T. Rogge, R. Yin, H. Wang, G. Sirvinskaite, L. Ackermann, "Late-Stage Diversification by Manganese-Catalyzed C–H Activation: Access to Acyclic, Hybrid and Stapled Peptides" Angew. Chem. Int. Ed. 2019, 58, 3476-3480. Abstract>

309) J. Loup,' V. Müller,' D. Ghorai, L. Ackermann, "Enantioselective Aluminum-Free Alkene Hydroarylations via C–H Activation by a Chiral Nickel/JoSPOphos Manifold" Angew. Chem. Int. Ed. 2019, 58, 1749-1753. ' Both authors contributed equally. Abstract>

308) Q. Bu,' E. Gonka,' K. Kucinski, L. Ackermann, "Cobalt-Catalyzed Hiyama-type C-H Activation with Arylsiloxanes: Versatile Access to Highly-Ortho-Decorated Biaryls" Chem. Eur. J. 2019, 25, 2213-2216. ' Both authors contributed equally. Abstract>

307) M. Tang, Y. Li, S. Han, L. Liu, L. Ackermann, J. J. Li, "Rhodium(III)-Catalyzed C-H Alkylation/Nucleophilic Addition Domino Reaction" Eur. J. Org. Chem. 2019, 660-664. Abstract>

306) J. Koeller, P. Gandeepan, L. Ackermann, "Visible-Light-Induced Decarboxylative C–H Adamantylation of Azoles at Ambient Temperature" Synthesis 2019, 51, 1284-1292. Abstract>

305) M. M. Lorion, N. Kaplaneris, J. Son, R. Kuniyil, L. Ackermann, "Late-Stage Peptide Diversification by Cobalt-Catalyzed C–H Activation: Sequential Multicatalysis for Stapled Peptides" Angew. Chem. Int. Ed. 2019, 58, 1684-1688. Abstract>

304) A. Bechtoldt, L. Ackermann, "Ruthenium(II)biscarboxylate-Catalyzed Hydrogen-Isotope Exchange by Alkene C–H Activation" ChemCatChem 2019, 11, 435-438. Abstract>

303) P. Gandeepan, L. Ackermann, "Organometallic Chelation-Assisted CH Functionalization", in Non-Noble Metal Catalysis: Molecular Approaches and Reactions (Eds.: R. J. Klein Gebbink, M.-E. Moret), Wiley-VCH, Weinheim, 2019, pp. 391-424. Abstract>

302) W. Ma, Z. Weng, X, Fang, L. Gu, Y. Song, L. Ackermann, "Ruthenium-Catalyzed C–H Selenylations of Benzamides" Eur. J. Org. Chem. 2019, 41-45. Abstract>

301) F. Yang, H. Zhang, X. Liu, B. Wang, L. Ackermann, "Transition Metal-Catalyzed Regio-Selective Aromatic C–H Bond Oxidation for C–O Bond Formation" Chin. J. Org. Chem. 2019, 39, 59-73. Abstract>


2018

300) H. Wang,' I. Choi,' T. Rogge, N. Kaplaneris, L. Ackermann, "Versatile and Robust C–C Activation by Chelation-Assisted Manganese-Catalysis" Nature Catal. 2018, 1, 993-1001. ' Both authors contributed equally Abstract>

299) D. Ghorai, L. H. Finger, G. Zanoni, L. Ackermann, "Bimetallic Nickel Complexes for Aniline C–H Alkylations" ACS Catal. 2018, 8, 11657-11662. Abstract>

298) S.-K. Zhang, R. C. Samanta, N. Sauermann, L. Ackermann, "Nickel-Catalyzed Electrooxidative C–H Amination: Support for Nickel(IV)" Chem. Eur. J. 2018, 24, 19166-19170. Abstract>

297) F. Pesciaioli, U. Dhawa, J. C. A. Oliveira, R. Yin, M. John, L. Ackermann, "Enantioselective Cobalt(III)-Catalyzed C–H Activation Enabled by Chiral Carboxylic Acid Cooperation" Angew. Chem. Int. Ed. 2018, 57, 15425-15429. ' Both authors contributed equally Abstract>

296) R. Mei, J. Koeller, L. Ackermann, "Electrochemical Ruthenium-Catalyzed Alkyne Annulations by C−H/Het−H Activation of Aryl Carbamates or Phenols in Protic Media" Chem. Commun. 2018, 54, 12879-12882. Abstract>

295) G. G. Dias, T. Rogge, R. Kuniyil, C. Jacob, R. F. S. Menna-Barreto, E. N. da Silva Júnior, L. Ackermann, "Ruthenium-catalyzed C–H oxygenation of quinones by weak O-coordination for potent trypanocidal agents" Chem. Commun. 2018, 54, 12840-12843. Abstract>

294) Y. Qiu,' M. Stangier,' T. H. Meyer, J. C. A. Oliveira, L. Ackermann, "Iridium-Catalyzed Electrooxidative C–H Activation by Chemo-Selective Redox-Catalyst Cooperation" Angew. Chem. Int. Ed. 2018, 57, 14179-14183. ' Both authors contributed equally Abstract>

293) Y.-F. Liang,' L. Yang,' T. Rogge,' L. Ackermann, "Ruthenium(IV) Intermediates in C−H Activation/Annulation by Weak O-Coordination" Chem. Eur. J. 2018, 24, 16548-16552. ' Both authors contributed equally Abstract>

292) T. H. Meyer, J. C. A. Oliveira, S. Chandra Sau, N. W. J. Ang, L. Ackermann, "Electrooxidative Allene Annulations by Mild Cobalt-Catalyzed C–H  Activation" ACS Catal. 2018, 8, 9140-9147. Abstract>

291) M. Virelli, E. Moroni, G. Colombo, L. Fiengo,  A. Porta, L. Ackermann, G. Zanoni, "Expedient Access to 2-Benzazepines by Palladium-Catalyzed C−H activation: Identification of a Unique HSP90 Inhibitor Scaffold" Chem. Eur. J. 2018, 24, 16516-16520. Abstract>

290) W. Wang,' M. M. Lorion,' O. Martinazzoli, L. Ackermann, "BODIPY Peptide Labeling by Late-Stage C(sp3)-H Activation" Angew. Chem. Int. Ed. 2018, 57, 10554-10558. ' Both authors contributed equally Abstract>

289) W. Wang,' M. M. Lorion,' J. Shah, A. R. Kapdi, L. Ackermann, "Late-Stage Peptide Diversification by Position- Selective C-H Activation" Angew. Chem. Int. Ed. 2018, 57, 14700-14717. ' Both authors contributed equally Abstract>

288) N. Sauermann, T. H. Meyer, Y. Qiu, L. Ackermann, "Electrocatalytic C–H Activation" ACS Catal. 2018, 8, 7086-7103. Abstract>

287) N. Sauermann, T. H. Meyer, L. Ackermann, "Electrochemical Cobalt-Catalyzed C–H Activation" Chem. Eur. J. 2018, 24, 16209-16217. Abstract>

286) Y.-F. Liang, R. Steinbock, L. Yang, L. Ackermann, "Continuous Visible Light-Photo-Flow Approach for Manganese-Catalyzed (Het)Arene C−H Arylation" Angew. Chem. Int. Ed. 2018, 57, 10625-10629. Abstract>

285) Y. Qiu,' J. Struwe,' T. H. Meyer, J. C. A. Oliveira, L. Ackermann, "Catalyst- and Reagent-free Electrochemical Azole C−H Amination" Chem. Eur. J. 2018, 24, 12784-12789. 'Both authors contributed equally Abstract>

284) S. R. Yetra,' Z. Shen,' H. Wang, L. Ackermann, "Thiocarbonyl-Enabled Ferrocene C–H Nitrogenation by Cobalt(III) Catalysis: Thermal and Mechanochemical" Beilstein J. Org. Chem. 2018, 14, 1546-1553. 'Both authors contributed equally Abstract>

283) R. Mei, N. Sauermann, J. C. A. Oliveira, L. Ackermann, "Electro-Removable Traceless Hydrazides for Cobalt-Catalyzed Electro-Oxidative C–H/N–H Activation with Internal Alkynes" J. Am. Chem. Soc. 2018140, 7913-7921. Abstract>

282) J. Mo,' T. Müller,' J. C. A. Oliveira, L. Ackermann, "1,4-Iron Migration for Expedient Allene Annulations through Iron-Catalyzed C–H/N–H/C–O/C–H Functionalizations" Angew. Chem. Int. Ed. 2018, 57, 7719-7723. 'Both authors contributed equally Abstract>

281) F. Ferlin, L. Luciani, S. Santoro, A. Marrocchi, D. Lanari, A. Bechtoldt, L. Ackermann, L. Vaccaro, "A continuous flow approach for the C–H functionalization of 1,2,3-triazoles in γ-valerolactone as biomass-derived medium" Green Chem. 2018, 20, 2888-2893. Abstract>

280) E. Detmar, V. Müller, D. Zell, L. Ackermann, M. Breugst, "Cobalt-Catalyzed C–H Cyanations: Insights into the Reaction Mechanism and the Role of London Dispersion" Beilstein J. Org. Chem. 2018, 14, 1537-1545. Abstract>

279) Y. Fang, T. Rogge, L. Ackermann, S.-Y. Wang, S.-J. Ji, "Nickel-catalyzed reductive thiolation and selenylation of unactivated alkyl bromides" Nature Commun. 2018, 9, 2240. Abstract>

278) E. N. da Silva Júnior, G. A. M. Jardim, R. S. Gomes, Y.-F. Liang, L. Ackermann, "Weakly-coordinating N-oxide and carbonyl groups for metal-catalyzed C–H activation: The case of A-ring functionalization" Chem. Commun. 2018, 54, 7398-7411. Abstract>

277) Y. Qiu,' W.-J. Kong,' J. Struwe, N. Sauermann, T. Rogge, A Scheremetjew, L. Ackermann, "Electrooxidative Rhodium-Catalyzed C–H/C–H Activation: Electricity as Oxidant for Cross-Dehydrogenative Alkenylation" Angew. Chem. Int. Ed. 2018, 57, 5828-5832. 'Both authors contributed equally Abstract> (highlighted in ChemistryViews)

276) J. Kalepu, P. Gandeepan, L. Ackermann, L. Pilarski, "C4-H Indole Functionalisation: Precedent and Prospects" Chem. Sci. 2018, 9, 4203-4216. Abstract>

275) S. Santoro, A. Marrocchi, D. Lanari, L. Ackermann, L. Vaccaro, "Towards Sustainable C–H Functionalization Reactions: The Emerging Role of Bio-Based Reaction Media" Chem. Eur. J. 2018, 24, 13383-13390. Abstract>

274) U. Dhawa, D. Zell, R. Yin, S. Okumura, M. Murakami, L. Ackermann, "C–H/C–F Functionalization by E-Selective Ruthenium(II)-Catalysis" J. Catal. 2018, 364, 14-18. Abstract>

273) C. Zhu, J. C. A. Oliveira, Z. Shen, H. Huang, L. Ackermann, "Manganese(II/III/I)-Catalyzed C–H Arylations in Continuous Flow" ACS Catal. 2018, 8, 4402-4407. Abstract>

272) Y. Qiu, C. Tian, L. Massignan, T. Rogge, L. Ackermann, "Electrooxidative Ruthenium-Catalyzed C–H/O–H Annulation by Weak O-Coordination" Angew. Chem. Int. Ed. 2018, 57, 5818-5822. Abstract>

271) N. Sauermann, R. Mei, L. Ackermann, "Electrochemical C–H Amination by Cobalt Catalysis in a Renewable Solvent" Angew. Chem. Int. Ed. 2018, 57, 5090-5094. Abstract>

270) Y.-F. Liang, R. Steinbock, A. Münch, D. Stalke, L. Ackermann, "Manganese-Catalyzed Carbonylative Annulations for Redox-Neutral Late-Stage Diversification" Angew. Chem. Int. Ed. 2018, 57, 5384-5388. Abstract>

269) Y.-F. Liang, L. Massignan, L. Ackermann, "Sustainable Manganese-Catalyzed C–H Activation/Hydroarylation of Imines" ChemCatChem 2018, 10, 2768-2772. Abstract>

268) F. Fumagalli, S. Warratz,  S.-K. Zhang, T. Rogge, C. Zhu, A. C. Stückl, L. Ackermann, "Arene-Ligand-free Ruthenium(II/III) Manifold for meta-C–H Alkylation: Remote Purine Diversification" Chem. Eur. J. 2018, 24, 3984-3988. Abstract>

267) C. Tian, L. Massignan, T. H. Meyer, L. Ackermann, "Electrochemical C–H/N–H Activation by Water-Tolerant Cobalt-Catalysis at Room Temperature" Angew. Chem. Int. Ed. 2018, 57, 2383-2387. Abstract>

266) A. Bechtoldt, M. E. Baumert, L. Vaccaro, L. Ackermann, "Ruthenium(II) oxidase catalysis for C–H alkenylations in biomass-derived γ-valerolactone" Green Chem. 2018, 20, 398-402. Abstract>

265) Q. Bu,' T. Rogge,' V. Kotek, L. Ackermann, "Distal Weak Coordination of Acetamides in Ruthenium(II)-Catalyzed C–H Activation Processes" Angew. Chem. Int. Ed. 2018, 57, 765-768. 'Both authors contributed equally. Abstract>

264) K. Korvorapun, N. Kaplaneris, T. Rogge, S. Warratz, A. C. Stückl, L. Ackermann, "Sequential meta-/ortho-C–H Functionalizations by One-Pot Ruthenium(II/III) Catalysis" ACS Catal. 2018, 8, 886-892. Abstract>

263) W. Ma, Z. Weng, T. Rogge, L. Gu, J. Lin, A. Peng, X. Luo, X. Gou, L. Ackermann, "Ruthenium-Catalyzed C–H Chalcogenation of Anilines" Adv. Synth. Catal. 2018, 360, 704-710. Abstract>

262) P. Gandeepan, L. Ackermann, "Transient Directing Groups for Transformative  C–H Activation by Synergistic Metal Catalysis" Chem 2018, 4, 199-222. Abstract>

261) M. Bauer,' W. Wang,' M. M. Lorion, C. Dong, L. Ackermann, "Internal Peptide Late-Stage Diversification: Peptide Isosteric Triazoles for Primary and Secondary C(sp3)–H Activation" Angew. Chem. Int. Ed. 2018, 57, 203-207. 'Both authors contributed equally. Abstract>

260) Catalytic Hydroarylation of Carbon-Carbon Multiple Bonds (Eds.: L. G. Habgood, T. B. Gunnoe, L. Ackermann), Wiley-VCH, Weinheim, 2018. ISBN: 978-3-527-34013-2 Content>


2017


259) N. Sauermann,' T. H. Meyer,' C. Tian, L. Ackermann, "Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature" J. Am. Chem. Soc. 2017, 139, 18452-18455. 'Both authors contributed equally. Abstract>

258) S. Nakanowatari,' T. Müller,' J. C. A. Oliveira, L. Ackermann, "Bifurcated Nickel-Catalyzed Functionalizations: Heteroarene C-H Activation with Allenes" Angew. Chem. Int. Ed. 2017, 56, 15891-15895. 'Both authors contributed equally. Abstract>

257) M. M. Lorion, K. Maindan, A. R. Kapdi, L. Ackermann, "Heteromultimetallic Catalysis for Sustainable Organic Syntheses" Chem. Soc. Rev. 2017, 46, 7399-7420. Abstract>

256) H. Wang,' F. Pesciaioli,' J. C. A. Oliveira, S. Warratz, L. Ackermann, "Synergistic Manganese(I) C-H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation" Angew. Chem. Int. Ed. 2017, 56, 15063-15067. 'Both authors contributed equally. Abstract>

255) J. Loup, D. Zell, J. C. A. Oliveira, H. Keil, D. Stalke, L. Ackermann, "Asymmetric Iron-Catalyzed C-H Alkylation Enabled by Remote Ligand meta-Substitution" Angew. Chem. Int. Ed. 2017, 56, 14197-14201. Abstract>

254) N. Y. P. Kumar, T. Rogge, S. R. Yetra, A. Bechtoldt, E. Clot, L. Ackermann, "Mild Decarboxylative C-H Alkylation: Computational Insights for Solvent-Robust Ruthenium(II) Domino Manifold" Chem. Eur. J. 2017, 23, 17449-17453. Abstract>

253) H. Huang, S. Nakanowatari, L. Ackermann, "Selectivity Control in Ruthenium(II)-Catalyzed C-H/N-O Activation with Alkynylbromides" Org. Lett. 2017, 19, 4620-4623. Abstract>

252) Z. Ruan, D. Ghorai, G. Zanoni, L. Ackermann, "Nickel-Catalyzed C-H Activation of Purine Bases with Alkyl Halides" Chem. Commun. 2017, 53, 9113-9116. Abstract>

251) R. Mei,' S.-K. Zhang,' L. Ackermann, "Concise Synthesis of Lamellarin Alkaloids by C-H/N-H Activation: Evaluation of Metal Catalysts in Oxidative Alkyne Annulation" Synlett 2017, 28, 1715-1718. 'Both authors contributed equally. Abstract>

250) W. Liu, G. Cera, J. C. A. Oliveira, Z. Shen, L. Ackermann, "MnCl2-Catalyzed C-H Alkylations with Alkyl Halides" Chem. Eur. J. 2017, 23, 11524-11528. Abstract>

249) D. Zell, M. Bursch, V. Müller, S. Grimme, L. Ackermann, "Switch of C-H Activation Mechanism for Full Selectivity Control in Cobalt(III)-Catalyzed C-H Alkylations" Angew. Chem. Int. Ed. 2017, 56, 10378-10382. Abstract>

248) D. Ghorai, V. Müller, H. Keil, D. Stalke, G. Zanoni, B. A. Tkachenko, Peter R. Schreiner, L. Ackermann, "Secondary Phosphine Oxide Preligand for Palladium-Catalyzed C-H (Hetero)Arylations: Efficient Access to Pybox Ligands" Adv. Synth. Catal. 2017, 359, 3137-3141. Abstract>

247) Z. Shen,' G. Cera,' T. Haven , L. Ackermann, "Tri-Substituted Triazole-Enabled C-H Activation of Benzyl and Aryl Amines by Iron-Catalysis" Org. Lett. 2017, 19, 3795-3798. 'Both authors contributed equally. Abstract>

246) D. Zell, V. Müller, U. Dhawa, M. Bursch, R. R. Presa, S. Grimme, L. Ackermann, "Mild Cobalt(III)-Catalyzed Allylative C-F/C-H Functionalizations at Room Temperature" Chem. Eur. J. 2017, 23, 12145-12148. Abstract> (highlighted in ChemistryViews)

245) Y.-F. Liang, V. Müller, W. Liu, A. Münch, D. Stalke, L. Ackermann, "Methylenecyclopropane Annulation by Manganese(I)-Catalyzed Stereoselective C-H/C-C Activation" Angew. Chem. Int. Ed. 2017, 56, 9415-9419. Abstract>

244) G. Cera,' T. Haven,' L. Ackermann, "Iron-Catalyzed C-H/N-H Activation by Triazole Guidance: Versatile Alkyne Annulation" Chem. Commun. 2017, 53, 6460-6463. 'Both authors contributed equally. Abstract>

243) Z. Zhang, S. Han, M. Tang, L. Ackermann, J. Li, "C-H Alkylations of (Hetero)Arenes by Maleimides and Maleate Esters through Cobalt(III) Catalysis" Org. Lett. 2017, 19, 3315-3318. Abstract>

242) R. Mei, S.-K. Zhang, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Alkynylation of Weakly-Coordinating Benzoic Acids" Org. Lett. 2017, 19, 3171-3174. Abstract>

241) P. Gandeepan, J. Mo, L. Ackermann, "Photo-induced Copper-Catalyzed C-H Chalcogenation of Azoles at Room Temperature" Chem. Commun. 2017, 53, 5906-5909. Abstract>

240) D. Zell, U. Dhawa, V. Müller, M. Bursch, S. Grimme, L. Ackermann, "C-F/C-H Functionalization by Manganese(I) Catalysis: Expedient (Per)Fluoro-Allylations and Alkenylations" ACS Catal. 2017, 7, 4209-4213. Abstract>

239) H. Wang,' M. M. Lorion,' L. Ackermann, "Air-Stable Manganese(I)-Catalyzed C-H Activation for Decarboxylative C-H/C-O Cleavages on H2O" Angew. Chem. Int. Ed. 2017, 56, 6339-6342. 'Both authors contributed equally. Abstract>

238) F. Ferlin, S. Santoro, L. Ackermann, L. Vaccaro, "Heterogeneous C-H Alkenylations in Continuous-Flow: Oxidative Palladium-Catalysis in a Biomass-Derived Reaction Medium" Green Chem. 2017, 19, 2510-2514. Abstract>

237) N. Sauermann, J. Loup, D. Kootz, A. Berkessel, L. Ackermann, "Triazolylidene Ligands Allow Cobalt-Catalyzed C-H/C-O Alkenylations at Ambient Temperature" Synthesis 2017, 49, 3476-3484. Abstract>

236) H. Wang, M. M. Lorion, L. Ackermann, "Domino C-H/N-H Allylations of Imidates by Cobalt Catalysis" ACS Catal. 2017, 7, 3420-3433. Abstract>

235) M. Moselage,' J. Li,' F. Kramm, L. Ackermann, "Ruthenium(II)-Catalyzed C-C Arylations and Alkylations: Decarbamoylative C-C Functionalizations" Angew. Chem. Int. Ed. 2017, 56, 5341-5344. 'Both authors contributed equally. Abstract>

234) J. Li,' K. Korvorapun,' S. De Sarkar,' T. Rogge, D. J. Burns, S. Warratz, L. Ackermann, "Ruthenium(II)-catalysed remote C-H alkylations as a versatile platform to meta-decorated arenes" Nature Commun. 2017, 8, 15430. 'Both authors contributed equally. Abstract>

233) T. H. Meyer,' W. Liu,' M. Feldt, A. Wuttke, R. A. Mata, L. Ackermann, "Manganese(I)-Catalyzed Dispersion-Enabled C-H/C-C Activation" Chem. Eur. J. 2017, 23, 5443-5447. 'Both authors contributed equally. Abstract>

232) W. Ma, P. Gandeepan, J. Li, L. Ackermann, "Recent advances in positional-selective alkenylations: Removable guidance for twofold C-H activation" Org. Chem. Front. 2017, 4, 1435-1467. Abstract>

231) S. Nakanowatari, R. Mei, M. Feldt, L. Ackermann, "Cobalt(III)-Catalyzed Hydroarylation of Allenes via C-H Activation" ACS Catal. 2017, 7, 2511-2515. Abstract>

230) G. Cera, T. Haven, L. Ackermann, "Iron-Catalyzed C-H Alkynylation through Triazole Assistance: Expedient Access to Bioactive Heterocycles" Chem. Eur. J. 2017, 23, 3577-3582. Abstract>

229) GK. Raghuvanshi, D. Zell, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Oxygenations of Reusable Sulfoximine Benzamides" Org. Lett. 2017, 19, 1278-1281. Abstract>

228) S. Santoro, F. Ferlin, L. Luciania, L. Ackermann, L. Vaccaro, "Biomass-derived solvents as effective media for cross-coupling reactions and C-H functionalization processes" Green Chem. 2017, 19, 1601-1612. Abstract>

227) Z. Ruan,' N. Sauermann,' E. Manoni, L. Ackermann, "Manganese-Catalyzed C-H Alkynylation: Expedient Peptide Synthesis and Modification" Angew. Chem. Int. Ed. 2017, 56, 3172-3176. 'Both authors contributed equally. Abstract>

226) Z. Ruan,' S.-K. Zhang,' C. Zhu, P. N. Ruth, D. Stalke, L. Ackermann, "Ruthenium(II)-Catalyzed meta C-H Mono- and Difluoromethylations by Phosphine/Carboxylate Cooperation" Angew. Chem. Int. Ed. 2017, 56, 2045-2049. 'Both authors contributed equally. Abstract>

225) P. Gandeepan, J. Koeller, L. Ackermann, "Expedient C-H Chalcogenation of Indolines and Indoles by Positional Selective Copper-Catalysis" ACS Catal. 2017, 7, 1030-1034. Abstract>

224) A. Schischko, H. Ren, N. Kaplaneris, L. Ackermann, "Bioorthogonal Diversification of Peptides by Selective Ruthenium(II)-Catalyzed C-H Activation" Angew. Chem. Int. Ed. 2017, 56, 1576-1580. Abstract> (highlighted in ChemistryViews)

223) S. Warratz, D. J. Burns, C. Zhu, K. Korvorapun, T. Rogge, J. Scholz, C. Jooss, D. Gelman, L. Ackermann, "meta-C-H Bromination on Purine Bases by Heterogeneous Ruthenium Catalysis" Angew. Chem. Int. Ed. 2017, 56, 1557-1560. Abstract>

222) S. Zhang, M. Tang, S. Han, L. Ackermann, J. Li, "Carboxylate Enhanced Rhodium(III)-Catalyzed Aryl C-H Alkylation with Conjugated Alkenes under Mild Conditions" J. Org. Chem. 2017, 82, 664-672. Abstract>

221) W. Ma, H. Dong, D. Wang, L. Ackermann, "Late-Stage Diversification of Non-Steroidal Anti-Inflammatory Drugs by Transition Metal-Catalyzed C-H Alkenylations, Thiolations and Selenylation" Adv. Synth. Catal. 2017, 359, 966-973. Abstract>

220) D. Tonin,' D. Zell,' V. Müller, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Methylation with Trifluoroborates" Synthesis 2017, 49, 127-134. 'Both authors contributed equally. Abstract>

219) S. De Sarkar,' N. Y. P. Kumar,' L. Ackermann, "Ruthenium(II)Biscarboxylate-Catalyzed Borylations of C(sp2)-H and C(sp3)-H Bonds" Chem. Eur. J. 2017, 23, 84-87. 'Both authors contributed equally. Abstract>

218) D. J. Burns, S. I. Kozhushkov, L. Ackermann, "Ruthenium Catalysts for the Alkylation of Functionalized Arenes and Heteroaromatic Substrates via Hydroarylation", in Catalytic Hydroarylation of Carbon-Carbon Multiple Bonds (Eds.: L. G. Habgood, T. B. Gunnoe, L. Ackermann), Wiley-VCH, Weinheim, 2017. Content>

217) M. M. Lorion, L. Ackermann, e-EROS 2017, DOI: 10.1002/047084289X.rn02097. Abstract>


2016


216) R. Mei,' C. Zhu,' Lutz Ackermann L. Ackermann, "Ruthenium(II)-Catalyzed C-H Functionalizations on Benzoic Acids with Aryl, Alkenyl and Alkynyl Halides by Weak-O-Coordination" Chem. Commun. 2016, 52, 13171-13174. 'Both authors contributed equally. Abstract>

215) W. Liu,' S. C. Richter,' R. Mei,' Milica Feldt, Lutz Ackermann L. Ackermann, "Synergistic Heterobimetallic Manifold for Expedient Manganese(I)-Catalyzed C-H Cyanation" Chem. Eur. J. 2016, 22, 17958-17961. 'Both authors contributed equally. Abstract>

214) Y.-F. Liang, L. Massignan, W. Liu, L. Ackermann, "Catalyst-Guided C=Het Hydroarylations via Manganese-Catalyzed Additive-Free C-H Activation" Chem. Eur. J. 2016, 22, 14856-14859. Abstract>

213) D. Santrač,' S. Cella,' W. Wang, L. Ackermann, "Palladium-Catalyzed C-H Arylation of Amides by Triazole Assistance" Eur. J. Org. Chem. 2016, 5429-5436. 'Both authors contributed equally. Abstract>

212) T. Müller, L. Ackermann, "Nickel-Catalyzed C-H Chalcogenation of Anilines" Chem. Eur. J. 2016, 22, 14151-14154. Abstract>

211) H. Wang,' M. M. Lorion,' L. Ackermann, "Overcoming the Limitations of C-H Activation with Strongly Coordinating N-Heterocycles by Cobalt Catalysis" Angew. Chem. Int. Ed. 2016, 55, 10386-10390. 'Both authors contributed equally. Abstract>

210) G. Cera, L. Ackermann, "Iron-Catalyzed C-H Functionalization Processes" Top. Curr. Chem. 2016, 374, 191-224. Abstract>

209) X. Tian, F. Yang, D. Rasina, M. Bauer, S. Warratz, F. Ferlin, L. Vaccaro, L. Ackermann, "C-H Arylations of 1,2,3-Triazoles by Reusable Heterogeneous Palladium Catalysts in Biomass-Derived γ-Valerolactone" Chem. Commun. 2016, 52, 9777-9780. Abstract>

208) Z. Ruan, S. Lackner, L. Ackermann, "Nickel-Catalyzed C-H Alkynylation of Anilines: Expedient Access to Functionalized Indoles and Purine Nucleobases" ACS Catal. 2016, 6, 4690-4693. Abstract>

207) J. Hubrich, L. Ackermann, "Amino Acid Ligands for Ruthenium(II)-Catalyzed C-H Arylation of Aryltetrazoles with Chlorides: Expedient Access to Antihypertension Drugs" Eur. J. Org. Chem. 2016, 3700-3704. Abstract>

206) W. Liu, L. Ackermann, "Manganese-Catalyzed C-H Activation" ACS Catal. 2016, 6, 3743-3752. Abstract>

205) D. Rasina, A. Kahler-Quesada, S. Ziarelli, S. Warratz, H. Cao, S. Santoro, L. Ackermann, L. Vaccaro, "Heterogeneous Palladium-Catalysed Catellani Reaction in Biomass-Derived γ-Valerolactone" Green Chem. 2016, 18, 5025-5030. Abstract>

204) T. Himmler, L. Rodefeld, J. Hubrich, L. Ackermann, "Method for producing biphenylamines from azobenzenes by ruthenium catalysis" WO 2016071249 A1 20160512, 2016.

203) J. Li, M. Tang, L. Zang, X. Zhang, Z. Zhang, L. Ackermann, "Amidines for Versatile Cobalt(III)-Catalyzed Synthesis of Isoquinolines through C-H Functionalization with Diazo Compounds" Org. Lett.2016, 18, 2742-2745. Abstract>

202) D. Zell,' Q. Bu,' M. Feldt, L. Ackermann, "Mild C-H/C-C Activation by (Z)-Selective Cobalt-Catalysis" Angew. Chem. Int. Ed. 2016, 55, 7408-7412. 'Both authors contributed equally. Abstract>

201) T. Himmler, L. Rodefeld, J. Hubrich, L. Ackermann, "Method for production of biphenylamines from azobenzenes using ruthenium catalysis" EP 3015452 A1 20160504, 2016.

200) R. Mei, L. Ackermann, "Cobalt-Catalyzed C-H Functionalizations by Imidate Assistance with Aryl and Alkyl Chlorides" Adv. Synth. Catal. 2016, 358, 2443-2448. Selected as VIP paper. Abstract>

199) G. Cera, L. Ackermann, "Weak O-Assistance Outcompeting Strong N,N-bidentate Directing Groups in Copper-Catalyzed C-H Chalcogenation" Chem. Eur. J. 2016, 22, 8475-8478. Abstract>

198) K. Raghuvanshi, D. Zell, K. Rauch, L. Ackermann, "Ketone-Assisted Ruthenium(II)-Catalyzed C-H Imidation: Access to Primary Aminoketones by Weak Coordination" ACS Catal. 2016, 6, 3172-3175. Abstract>

197) W. Liu, S. C. Richter, Y. Zhang, L. Ackermann, "Manganese(I)-Catalyzed Substitutive C-H Allylation" Angew. Chem. Int. Ed. 2016, 55, 7747-7750. Abstract>

196) S. Fenner, L. Ackermann, "C-H Carboxylation of heteroarenes with ambient CO2" Green Chem. 2016, 18, 3804-3807. Abstract>

195) S. Santoro, S. I. Kozhushkov, L. Ackermann, L. Vaccaro, "Heterogeneous Catalytic Approaches in C-H Activation Reactions" Green Chem. 2016, 18, 3471-3493. Abstract>

194) R. Mei, H. Wang, S. Warratz, S. A. Macgregor, L. Ackermann, "Cobalt-Catalyzed Oxidase C-H/N-H Alkyne Annulation: Mechanistic Insights and Access to anti-Cancer Agents" Chem. Eur. J. 2016, 22, 6759-6763. Abstract>

193) H. Wang, M. Moselage, M. J. González, L. Ackermann, "Selective Synthesis of Indoles by Cobalt(III)-Catalyzed C-H/N-O Functionalization with Nitrones" ACS Catal. 2016, 6, 2705-2709. Abstract>

192) N. Y. P. Kumar,' A. Bechtoldt,' K. Raghuvanshi, L. Ackermann, "Ruthenium(II)-Catalyzed Decarboxylative C-H-Activation: Versatile Routes to meta-Alkenylated Arenes" Angew. Chem. Int. Ed. 2016, 55, 6929-6932. 'Both authors contributed equally. Abstract> (highlighted in Nature Chem.)

191) F. Yang, J. Koeller, L. Ackermann, "Photo-Induced Copper-Catalyzed C-H Arylation at Room Temperature" Angew. Chem. Int. Ed. 2016, 55, 4759-4762. Abstract>(Selected as hot paper)

190) Z. Ruan,' S. Lackner,' L. Ackermann, "A General Strategy for Nickel-Catalyzed C-H Alkylation of Anilines" Angew. Chem. Int. Ed. 2016, 55, 3153-3157. 'Both authors contributed equally. Abstract> (Selected as hot paper)

189) R. Mei,' J. Loup,' L. Ackermann, "Oxazolinyl-Assisted C-H Amidation by Cobalt(III) Catalysis" ACS Catal. 2016, 6, 793-797. 'Both authors contributed equally. Abstract>

188) G. Cera, T. Haven, L. Ackermann, "Expedient Iron-Catalyzed C-H Allylation/Alkylation by Triazole Assistance with Ample Scope" Angew. Chem. Int. Ed. 2016, 55, 1484-1488. Abstract>

187) D. Zell,' S. Warratz,' D. Gelman, S. J. Garden, L. Ackermann, "Single-Component Phosphinous Acid Ruthenium(II) Catalysts for Versatile C-H Activations by Metal-Ligand Cooperation" Chem. Eur. J. 2016, 22, 1248-1252. 'Both authors contributed equally. Abstract>

186) M. Moselage, J. Li, L. Ackermann, "Cobalt-Catalyzed C-H Activation" ACS Catal. 2016, 6, 498-525. Abstract>

185) C. Borie, L. Ackermann, M. Nechab, "Enantioselective syntheses of indanes: from organocatalysis to C-H functionalization" Chem. Soc. Rev. 2016, 45, 1368-1386. Abstract>

184) A. Bechtoldt, C. Tirler, K. Raghuvanshi, S. Warratz, C. Kornhaaß, L. Ackermann, "Ruthenium Oxidase Catalysis for Site-Selective C-H Alkenylations with Ambient O2 as the Sole Oxidant" Angew. Chem. Int. Ed. 2016, 55, 264-267. Abstract>

183) J. Li, S. De Sarkar, L. Ackermann, "meta- and para-Selective C-H Functionalization by C-H Activation" Top. Organomet. Chem. 2016, 55, 217-257. Abstract>


2015


182) N. Sauermann, M. J. González, L. Ackermann, "Cobalt(III)-Catalyzed C-H Alkynylation with Bromoalkynes under Mild Conditions" Org. Lett. 2015, 17, 5316-5319. Abstract>

181) J. Li, S. Warratz, D. Zell, S. De Sarkar, E. E. Ishikawa, L. Ackermann, "N-Acyl Amino Acid Ligands for Ruthenium(II)-catalyzed meta-C-H tert-Alkylation with Removable Auxiliaries" J. Am. Chem. Soc. 2015, 137, 13894-13901. Abstract>(highlighted in ACS Cent. Sci.)

180) T. Himmler, L. Rodefeld, J. Hubrich, L. Ackermann, "Method for producing biphenylamines from anilides by ruthenium catalysis" WO 2015162144 A1 20151029 2015.

179) W. Liu, J. Bang, Y. Zhang, L. Ackermann, "Manganese(I)-Catalyzed C-H Aminocarbonylation of Heteroarenes" Angew. Chem. Int. Ed. 2015, 54, 14137-14140. Abstract>(highlighted in Synfacts 2015, 1253)

178) H. Wang, J. Koeller, W. Liu, L. Ackermann, "Cobalt(III)-Catalyzed C-H/N-O Functionalizations: Isohypsic Access to Isoquinolines" Chem. Eur. J. 2015, 21, 15525-15528. Abstract>

177) T. Niklas, C. Steinmetzger, W. Liu, D. Zell, D. Stalke, L. Ackermann, M. John, "Determination of the Relative Configuration of β-Amino Acid Esters Based on Residual Dipolar Couplings" Eur. J. Org. Chem. 2015, 6801-6805. Abstract>

176) S. Nakanowatari, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Functionalizations with Allenes: Versatile Allenylations and Allylations" Chem. Eur. J. 2015, 21, 16246-16251. Abstract>

175) J. Li, L. Ackermann, "C-H activation: Following directions" Nat. Chem. 2015, 7, 686-687. Abstract>

174) J. Li, L. Ackermann, "Carboxylate-Assisted Ruthenium(II)-Catalyzed C-H Activations of Monodentate Amides with Conjugated Alkenes" Org. Chem. Front. 2015, 2, 1035-1039. Abstract>

173) S. Musa, A. Ghosh, L. Vaccaro, L. Ackermann, D. Gelman, "Efficient E-Selective Transfer Semihydrogenation of Alkynes by Means of Ligand-Metal Cooperating" Adv. Synth. Catal. 2015, 357, 2351-2357. Abstract>

172) J. Hubrich, T. Himmler, L. Rodefeld, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Arylation of Azoarenes by Carboxylate Assistance" ACS Catal. 2015, 5, 4089-4093. Abstract>

171) J. Li, L. Ackermann, "Cobalt(III)-Catalyzed Aryl and Alkenyl C-H Aminocarbonylation with Isocyanates and Acyl Azides" Angew. Chem. Int. Ed. 2015, 54, 8551-8554. Abstract>

170) Y. Zhu, M. Bauer, L. Ackermann, "Late-Stage Peptide Diversification by Bioorthogonal Catalytic C-H Arylation at 23 °C in H2O" Chem. Eur. J. 2015, 21, 9980-9983. Abstract>

169) L. Wang, K. Rauch, A. V. Lygin, S. I. Kozhushkov, L. Ackermann, "Ruthenium-Catalyzed Direct Oxidative Alkenylation of Arenes by Twofold C-H Bond Functionalization in Water: Synthesis of Ethyl (E)-3-(2-Acetamido-4-methylphenyl)acrylate" Org. Synth. 2015, 92, 131-147. Abstract>

168) K. Graczyk, T. Haven, L. Ackermann, "Iron-Catalyzed C(sp2)-H and C(sp3)-H Methylations of Amides and Anilides" Chem. Eur. J. 2015, 21, 8812-8815. Abstract>

167) M. Moselage, N. Sauermann, J. Koeller, W. Liu, D. Gelman, L. Ackermann, "Cobalt(III)-Catalyzed Allylation with Allyl Acetates by C-H/C-O Cleavage" Synlett 2015, 1596-1600. Abstract>

166) W. Ma, L. Ackermann, "Cobalt(II)-Catalyzed Oxidative C-H Alkenylations: Regio- and Site-Selective Access to Isoindolin-1-one" ACS Catal. 2015, 5, 2822-2825. Abstract>

165) M. Moselage, N. Sauermann, S. C. Richter, L. Ackermann, "C-H Alkenylations with Alkenyl Acetates, Phosphates, Carbonates and Carbamates by Versatile Cobalt Catalysis at 23 °C" Angew. Chem. Int. Ed. 2015, 54, 6352-6355. Abstract> (Selected as hot paper)

164) S. Warratz,' C. Kornhaaß,' A. Cajaraville, B. Niepötter, D. Stalke, L. Ackermann "Ruthenium(II)-Catalyzed C-H Activation/Alkyne Annulation with O2 as the Sole Oxidant by Weak-Coordination" Angew. Chem. Int. Ed. 2015, 54, 5513-5517. 'Both authors contributed equally. Abstract>(Selected as hot paper)

163) J. Li, L. Ackermann, "Cobalt-Catalyzed C-H Arylations with Weakly-Coordinating Amides and Tetrazoles: Expedient Route to Angiotensin-II-Receptor Blockers" Chem. Eur. J. 2015, 21, 5718-5722. Abstract>

162) C. Tirler, L. Ackermann, "Ruthenium(II)-Catalyzed Cross-Dehydrogenative C-H Alkenylations by Triazole Assistance" Tetrahedron (Symposia in print) 2015, 4543-4551. Abstract>

161) W. Liu, D. Zell, M. John, L. Ackermann, "Manganese-Catalyzed Synthesis of cis-β-Amino Acid Esters through Organometallic C-H Activation of Ketimines" Angew. Chem. Int. Ed. 2015, 54, 4092-4096. Abstract>

160) L. Ackermann, "Robust Ruthenium(II)-Catalyzed C-H Arylations: Carboxylate Assistance for the Efficient Synthesis of Angiotensin-II-Receptor Blockers" Org. Process Res. Dev. 2015, 18, 260-269. Abstract>

159) J. Li, L. Ackermann, "Cobalt-Catalyzed C-H Cyanation of Arenes and Heteroarenes" Angew. Chem. Int. Ed. 2015, 54, 3635-3638. Abstract> (Selected as hot paper)

158) J. Hubrich, T. Himmler, L. Rodefeld, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Arylation of Anilides with Boronic Acids, Borinic Acids and Potassium Trifluoroborates" Adv. Synth. Catal. 2015, 357, 474-480. Abstract>

157) K. Raghuvanshi, K. Rauch, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Acyloxylation of Phenols with Removable Auxiliary" Chem. Eur. J. 2015, 21, 1790-1794. Abstract>


2014


156) F. Yang, L. Ackermann, "Dehydrative C-H/N-OH Functionalizations in H2O by Ruthenium(II)-Catalysis: Subtle Effect of Carboxylate Ligands and Mechanistic Insight" J. Org. Chem. 2014, 79, 12070-12082. Abstract>

155) W. Ma, R. Mei, G. Tenti, L. Ackermann, "Ruthenium(II)-Catalyzed Oxidative C-H Alkenylations of Sulfonic Acids, Sulfonyl Chlorides and Sulfonamides" Chem. Eur. J. 2014, 20, 15248-15251. Abstract>

154) F. Yang, K. Rauch, K. Kettelhoit, L. Ackermann, "Aldehyde-Assisted Ruthenium(II)-Catalyzed C-H Oxygenations" Angew. Chem. Int. Ed. 2014, 53, 11285-11288. Abstract> (Selected as hot paper)

153) Y. Zhu, M. Bauer, J. Ploog, L. Ackermann, "Late-Stage Diversification of Peptides by Metal-free C-H Arylation" Chem. Eur. J. 2014, 20, 13099-13102. Abstract>

152) S. De Sarkar, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Activation with Isocyanates: Versatile Route to Phthalimides" Chem. Eur. J. 2014, 20, 13932-13936. Abstract>

151) L. Ackermann, "Cobalt-Catalyzed C-H Arylations, Benzylations and Alkylations with Organic Electrophiles and Beyond" J. Org. Chem. 2014, 79, 8948-8954. Abstract>

150) H. H. Al Mamari, E. Diers, L. Ackermann, "Triazole-Assisted Ruthenium-Catalyzed C-H Arylation of Aromatic Amides" Chem. Eur. J. 2014, 20, 9739-9743. Abstract>

149) S. De Sarkar, W. Liu, S. I. Kozhushkov, L. Ackermann, "Weakly-Coordinating Directing Groups for Ruthenium(II)-Catalyzed C-H Activation" Adv. Synth. Catal. 2014, 356, 1461-1479. Abstract>

148) W. Ma, L. Ackermann, "Silver-Mediated Alkyne Annulations by C-H/P-H Functionalizations: Step-Economical Access to Benzophospholes" Synthesis 2014, 2297-2304. Abstract>

147) S. Nakanowatari, L. Ackermann, "Ruthenium(II)-Catalyzed Synthesis of Isochromenes by C-H Activation with Weakly-Coordinating Aliphatic Hydroxyl Groups" Chem. Eur. J. 2014, 20, 5409-5413. Abstract>

146) M. Schinkel, L. Wang, K. Bielefeld, L. Ackermann, "Ruthenium(II)-Catalyzed C(sp3)-H α-Alkylation of Pyrrolidines" Org. Lett. 2014, 16, 1876-1879. Abstract>

145) Q. Gu, H. H. Al Mamari, K. Graczyk, E. Diers, L. Ackermann, "Iron-Catalyzed C(sp2)-H and C(sp3)-H Arylation by Triazole Assistance" Angew. Chem. Int. Ed. 2014, 53, 3868-3871. Abstract> (highlighted in Synfacts) 2014, 735

144) C. Kornhaaß, C. Kuper, L. Ackermann, "Ferrocenylalkynes for Ruthenium-Catalyzed Isohypsic C-H/N-O Bond Functionalizations" Adv. Synth. Catal. 2014, 356, 1619-1624. Abstract>

143) J. Li, M. John, L. Ackermann, "Amidines for Versatile Ruthenium(II)-Catalyzed Oxidative C-H Activations with Internal Alkynes and Acrylates" Chem. Eur. J. 2014, 20, 5403-5408. Abstract>

142) W. Liu, L. Ackermann, "Versatile Ruthenium(II)-Catalyzed C-H Cyanations of Benzamides" Chem. Commun. 2014, 50, 1878-1881. Abstract>

141) W. Song, S. Lackner, L. Ackermann, "Nickel-Catalyzed C-H Alkylations: Direct Secondary Alkylations and Trifluoroethylations of Arenes" Angew. Chem. Int. Ed. 2014, 53, 2477-2480. Abstract> (Selected as hot paper)

140) A. Masarwa, D. Didier, T. Zabrodski, M. Schinkel, L. Ackermann, I. Marek, "Merging allylic carbon-hydrogen and selective carbon-carbon bond activation" Nature 2014, 505, 199-203. Abstract>

139) K. C. Mondal, P. P. Samuel, Y. Li, H. W. Roesky, S. Roy, L. Ackermann, N. S. Sidhu, G. M. Sheldrick, E. Carl, S. Demeshko, S. De, P. Parameswaran, L. Ungur, L. F. Chibotaru, D. M. Andrada, "A Catalyst with Two-Coordinate Nickel: Theoretical and Catalytic Studies" Eur. J. Inorg. Chem. 2014, 818-823. Abstract>

138) L. Ackermann, "Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C-H/Het-H Bond Functionalizations" Acc. Chem. Res. 2014, 47, 281-295. Abstract>

137) L. Wang, L. Ackermann, "Ruthenium-Catalyzed ortho-C-H Halogenations of Benzamides" Chem. Commun. 2014, 50, 1083-1085. Abstract>

136) V. S. Thirunavukkarasu, S. I. Kozhushkov, L. Ackermann, "C-H Nitrogenation and Oxygenation by Ruthenium Catalysis" Chem. Commun. 2014, 50, 29-39. Abstract>

135) J. Li, L. Ackermann, "Ruthenium-Catalyzed Oxidative Alkyne Annulation by C-H Activation on Ketimines" Tetrahedron 2014, 70, 3342-3348. Abstract>


2013


134) S. Musa, O. A. Filippov, N. V. Belkova, E. S. Shubina, G. A. Silantyev, L. Ackermann, D. Gelman, "Ligand-Metal Cooperating PC(sp3)P Pincer Complexes as Catalysts in Olefin Hydroformylation" Chem. Eur. J. 2013, 19, 16906-16909. Abstract>

133) S. Musa, L. Ackermann, D. Gelman, "Dehydrogenative Cross-Coupling of Primary and Secondary Alcohols" Adv. Synth. Catal. 2013, 355, 3077-3080. Abstract>

132) W. Ma, L. Ackermann, "Ruthenium(II)-Catalyzed C-H Alkenylations of Phenols with Removable Directing Groups" Chem. Eur. J. 2013, 19, 13925-13928. Abstract>

131) M. Schinkel, J. Wallbaum, S. I. Kozhushkov, I. Marek, L. Ackermann, "Carboxylate-Assistance for Catalyzed Hydroarylations of Methylenecyclopropanes" Org. Lett. 2013, 15, 4482-4484. Abstract>

130) B. Punji, W. Song, G. A. Shevchenko, L. Ackermann, "Cobalt-Catalyzed C-H Bond Functionalizations with Aryl and Alkyl Chlorides" Chem. Eur. J. 2013, 19, 10605-10610. Abstract> (highlighted in ChemistryViews)

129) W. Liu, L. Ackermann, "Ortho- and Para-Selective Ruthenium-Catalyzed C(sp2)-H Oxygenations of Phenol Derivatives" Org. Lett. 2013, 15, 3484-3486. Abstract>

128) W. Song, L. Ackermann, "Nickel-Catalyzed Alkyne Annulation by Anilines: Versatile Indole Synthesis by C-H/N-H Functionalization" Chem. Commun. 2013, 49, 6638-6640. Abstract>

127) V. S. Thirunavukkarasu, K. Raghuvanshi, L. Ackermann, "Expedient C-H Amidations of Heteroaryl Arenes Catalyzed by Versatile Ruthenium(II) Catalysts" Org. Lett. 2013, 15, 3286-3289. Abstract>

126) W. Song, S. I. Kozhushkov, L. Ackermann, "Site-Selective Catalytic C(sp2)-H Bond Azidations" Angew. Chem. Int. Ed. 2013, 52, 6576-6578. Abstract>

125) N. Y. P. Kumar, R. Jeyachandran, L. Ackermann, "C(sp3)-H Bond Arylations Catalyzed by Well-Defined [Ru(O2CMes)2(p-cymene)]" J. Org. Chem. 2013, 78, 4145-4152.Abstract>

124) N. Hofmann, L. Ackermann, "meta-Selective C-H Bond Alkylation with Secondary Alkyl Halides" J. Am. Chem. Soc. 2013, 135, 5877-5884.Abstract> (highlighted in Angewandte Chemie)

123) M. Schinkel, I. Marek, L. Ackermann, "Carboxylate-Assisted Ruthenium(II)-Catalyzed Hydroarylations of Unactivated Alkenes via C-H Cleavage" Angew. Chem. Int. Ed. 2013, 52, 3977-3980. Abstract>

122) F. Yang, L. Ackermann, "Ruthenium-Catalyzed C-H Oxygenation on Aryl Weinreb Amides" Org. Lett. 2013, 15, 718-720. Abstract>

121) E. Diers, N. Y. P. Kumar, T. Mejuch, I. Marek, L. Ackermann, "Carboxylate-assisted ruthenium(II)-catalyzed C-H arylations of 5-aryl tetrazoles: Step-economical access to Valsartan" Tetrahedron 2013, 69, 4445-4453. Abstract>

120) L. Wang, L. Ackermann, "Versatile Pyrrole Synthesis through Ruthenium(II)-Catalyzed Alkene C-H Bond Functionalization on Enamines" Org. Lett. 2013, 15, 176-179. Abstract>

119) S. I. Kozhushkov, L. Ackermann, "Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C-H bond functionalization" Chem. Sci. 2013, 4, 886-896. Abstract>

118) S. I. Kozhushkov, H. K. Potukuchi, L. Ackermann, "Direct C-H bond arylations and alkenylations with phenol-derived fluorine-free electrophiles" Catal. Sci. Technol. 2013, 3, 562-571. Abstract>

117) M. Deponti, S. I. Kozhushkov, D. S. Yufit, L. Ackermann, "Ruthenium-catalyzed C-H/O-H and C-H/N-H bond functionalizations: Oxidative annulations of cyclopropyl-substituted alkynes" Org. Biomol. Chem. 2013, 11, 142-148. Abstract>


2012


116) W. Ma, K. Graczyk, L. Ackermann, "Ruthenium-Catalyzed Alkyne Annulations with Substituted 1H-Pyrazoles by C-H/N-H Bond Functionalizations" Org. Lett. 2012, 14, 6318-6321. Abstract>

115) V. S. Thirunavukkarasu, L. Ackermann, "Ruthenium-Catalyzed C-H Bond Oxygenations with Weakly-Coordinating Ketones" Org. Lett. 2012, 14, 6206-6209. Abstract>

114) J. Li, C. Kornhaaß, L. Ackermann, "Ruthenium-catalyzed oxidative C-H alkenylation of aryl carbamates" Chem. Commun. 2012, 48, 11343-11345. Abstract>

113) C. Kornhaaß, J. Li, L. Ackermann, "Cationic Ruthenium Catalysts for Alkyne Annulations with Oximes by C-H/N-O Functionalizations" J. Org. Chem. 2012, 77, 9190-9198. Abstract>

112) R. Jeyachandran, H. K. Potukuchi, L. Ackermann, "Copper-Catalyzed CuAAC/Intramolecular C-H Arylation Sequence: Synthesis of Annulated 1,2,3-Triazoles" Beilstein J. Org. Chem. 2012, 8, 1771-1777. Abstract>

111) V. S. Thirunavukkarasu, J. Hubrich, L. Ackermann, "Ruthenium-Catalyzed Oxidative C(sp2)-H Bond Hydroxylation: Site-Selective C-O Bond Formation on Benzamides" Org. Lett. 2012, 14, 4210-4213. Abstract>

110) L. Ackermann, S. I. Kozhushkov, D. S. Yufit, "Ruthenium-Catalyzed Hydroarylations of Methylenecyclopropanes through C-H Bond Cleavages: Scope and Mechanism" Chem. Eur. J. 2012, 18, 12068-12077. Abstract>

109) K. Graczyk, W. Ma, L. Ackermann, "Oxidative Alkenylation of Aromatic Esters by Ruthenium-Catalyzed Twofold C-H Bond Cleavages" Org. Lett. 2012, 14, 4110-4113. Abstract> (highlighted in Synfacts 2012 1222)

108) W. Song, L. Ackermann, "Cobalt-Catalyzed Direct Arylation and Benzylation by C-H/C-O Cleavage with Sulfamates, Carbamates, and Phosphates" Angew. Chem. Int. Ed. 2012, 51, 8251-8254. Abstract>

107) V. S. Thirunavukkarasu, M. Donati, L. Ackermann, "Hydroxyl-Directed Ruthenium-Catalyzed C-H Bond Functionalization: Versatile Access to Fluorescent Pyrans" Org. Lett. 2012, 14, 3416-3419. Abstract> (highlighted in Synfacts 2012 1015)

106) L. Ackermann, V. P. Mehta, "Palladium-Catalyzed Mono-α-Arylation of Acetone with Aryl Imidazolylsulfonates" Chem. Eur. J. 2012, 18, 10230-10233. Abstract>

105) L. Ackermann, J. Pospech, H. K. Potukuchi, "Well-Defined Ruthenium(II) Carboxylate as Catalyst for Direct C-H/C-O Bond Arylations with Phenols in Water" Org. Lett. 2012, 14, 2146-2149. Abstract>

104) L. Ackermann, C. Kornhaaß, Y. Zhu, "Palladium-Catalyzed Direct C-H Bond Alkynylations of Heteroarenes Using gem-Dichloroalkenes" Org. Lett. 2012, 14, 1824-1826. Abstract>

103) L. Ackermann, E. Diers, A. Manvar, "Ruthenium-Catalyzed C-H Bond Arylations of Arenes Bearing Removable Directing Groups via Six-Membered Ruthenacycles" Org. Lett. 2012, 14, 1154-1157. Abstract> (Featured on Synform 06/12)

102) L. Ackermann, A. R. Kapdi, H. K. Potukuchi, S. I. Kozhushkov "Syntheses via C-H Bond Functionalizations", in Handbook of Green Chemistry (Volume-Eds.: C.-J. Li), Wiley-VCH, 2012, Weinheim, 259-305.

101) L. Ackermann, J. Pospech, K. Graczyk, K. Rauch, "Versatile Synthesis of Isocoumarins and α-Pyrones by Ruthenium-Catalyzed Oxidative C-H/O-H Bond Cleavages" Org. Lett. 2012, 14, 930-933. Abstract>

100) L. Ackermann, A. V. Lygin, "Cationic Ruthenium(II) Catalysts for Oxidative C-H/N-H Bond Functionalizations of Anilines with Removable Directing Group: Synthesis of Indoles in Water" Org. Lett. 2012, 14, 764-767. Abstract>

99) L. Ackermann, L. Wang, R. Wolfram, A. V. Lygin, "Ruthenium-Catalyzed Oxidative C-H Alkenylations of Anilides and Benzamides in Water" Org. Lett. 2012, 14, 728-731. Abstract>

98) L. Ackermann, L. Wang, A. V. Lygin, "Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles" Chem. Sci. 2012, 3, 177-180. Abstract> (highlighted by the Royal Society of Chemistry)


2011


97) L. Ackermann, S. Fenner, "Ruthenium-Catalyzed C-H/N-O Bond Functionalization: Green Isoquinolone Syntheses in Water" Org. Lett. 2011, 13, 6548-6551. Abstract>

96) L. Ackermann, B. Punji, W. Song, "User-Friendly [(diglyme)NiBr2]-Catalyzed Direct Alkylations of Heteroarenes with Unactivated Alkyl Halides through C-H Bond Cleavages" Adv. Synth. Catal. 2011, 353, 3325-3329.Abstract>

95) L. Ackermann, J. Pospech, "Ruthenium-Catalyzed Oxidative C-H Bond Alkenylations in Water: Expedient Synthesis of Annulated Lactones" Org. Lett. 2011, 13, 4153-4155.Abstract> (highlighted in Synfacts 2011, 1167)

94) L. Ackermann, A. V. Lygin, N. Hofmann, "Ruthenium-Catalyzed Oxidative Annulation via C-H/N-H Bond Cleavages" Angew. Chem. 2011, 123, 6503-6506; Angew. Chem. Int. Ed. 2011, 50, 6379-6382.Abstract> (selected as hot paper)

93) L. Ackermann, A. V. Lygin, "Ruthenium-Catalyzed Direct C-H Bond Arylations of Heteroarenes" Org. Lett. 2011, 13, 3332-3335.Abstract>

92) L. Ackermann, A. V. Lygin, N. Hofmann, "Ruthenium-Catalyzed Oxidative Synthesis of 2-Pyridones through C-H/N-H Bond Functionalizations" Org. Lett. 2011, 13, 3278-3281.Abstract> (highlighted in Synfacts 2011, 837)

91) L. Ackermann, S. Barfüßer, C. Kornhaaß, A. R. Kapdi, "C-H Bond Arylations and Benzylations on Oxazol(in)es with a Palladium Catalyst of a Secondary Phosphine Oxide" Org. Lett. 2011, 13, 3082-3085. Abstract>

90) L. Ackermann, S. I. Kozhushkov, D. S. Yufit, I. Marek, "Efficient Bronsted Acid Catalyzed Hydrations and Hydroaminations of (Dicyclopropylmethylene)cyclopropane" Synlett 2011, 1515-1518. Abstract>

89) L. Ackermann, M. Dell'Acqua, S. Fenner, R. Vicente, R. Sandmann, "Metal-Free Direct Arylations of Indoles and Pyrroles with Diaryliodonium Salts" Org. Lett. 2011, 13, 2358-2360. Abstract>

88) L. Ackermann, "Transition-Metal-Catalyzed Carboxylation of C-H Bonds" Angew. Chem. 2011, 123, 3926-3928; Angew. Chem. Int. Ed. 2011, 50, 3842-3844. Abstract>

87) L. Ackermann, N. Hofmann, R. Vicente, "Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines" Org. Lett. 2011, 13, 1875-1877. Abstract>

86) L. Ackermann, "Carboxylate-Assisted Transition Metal-Catalyzed C-H Bond Functionalizations: Mechanism and Scope" Chem. Rev. 2011, 111, 1315-1345. Abstract>

85) L. Ackermann, R. Sandmann, W. Song, "Palladium- and Nickel-Catalyzed Aminations of Aryl Imidazolylsulfonates and Sulfamates" Org. Lett. 2011, 13, 1784-1786.Abstract>

84) L. Ackermann, A. R. Kapdi, S. Fenner, C. Kornhaaß, C. Schulzke, "Well-Defined Air-Stable Palladium HASPO-Complexes for Efficient Kumada-Corriu Cross-Couplings of (Hetero)Aryl or Alkenyl Tosylates" Chem. Eur. J. 2011, 17, 2965-2971.Abstract>

83) L. Ackermann, H. K. Potukuchi, "1,3-Bis-(2,6-diisopropylphenyl)-[1,3,2]diazaphospholidine 2-oxide" e-EROS 2011, DOI: 10.1002/047084289X.rn01344.Abstract>

82) L. Ackermann, W. Song, R. Sandmann, "Nickel-Catalyzed, Base-Mediated Amination/Hydroamination Reaction Sequence for a Modular Synthesis of Indoles" J. Organomet. Chem. 2011, 696, 195-201.Abstract>

81) L. Ackermann, S. Fenner, "Direct Arylations of Electron-Deficient (Hetero)Arenes with Aryl or Alkenyl Tosylates and Mesylates" Chem. Commun. 2011, 47, 430-432.Abstract>

80) A. Wolpers, L. Ackermann, P. Vana, "H-Phosphonic Acid Derivatives as Catalysts for Reversible Chain Transfer Catalyzed Polymerization (RTCP) at Ambient and High Pressure" Macromol. Chem. and Phys. 2011, 212, 259-265.Abstract>


2010


79) L. Ackermann, "Air-Stable Bifunctional HASPO Preligands for Metal-Catalyzed Cross-Couplings and Direct C-H Bond Arylations" Isr. J. Chem. 2010, 50, 652-663.Abstract>

78) L. Ackermann, R. Vicente, H. K. Potukuchi, V. Pirovano, "Mechanistic Insight into Direct Arylations with Ruthenium(II) Carboxylate Catalysts" Org. Lett. 2010, 12, 5032-5035. Abstract>

77) L. Ackermann, H. K. Potukuchi, "Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C-H bond functionalization nexus", Org. Biomol. Chem. 2010, 8, 4503-4513.Abstract>

76) L. Ackermann, "Metal-catalyzed direct alkylations of (hetero)arenes via C-H bond cleavages with unactivated alkyl halides", Chem. Commun. 2010, 46, 4866-4877.Abstract>

75) L. Ackermann, R. Vicente, "Ruthenium-Catalyzed Direct Arylations through C-H Bond Cleavages" Top. Curr. Chem. 2010, 292, 211-229.Abstract>

74) L. Ackermann, A. R. Kapdi, C. Schulzke, "Air-Stable Secondary Phosphine Oxide or Chloride (Pre)Ligands for Cross-Couplings of Unactivated Alkyl Chlorides" Org. Lett. 2010, 12, 2298-2301. Abstract>

73) L. Ackermann, P. Novák, R. Vicente, V. Pirovano, H. K. Potukuchi, "Ruthenium-Catalyzed C-H Bond Functionalizations of 1,2,3-Triazol-4-yl-Substituted Arenes: Dehydrogenative Couplings Versus Direct Arylations" Synthesis 2010, 2245-2253. Abstract>

72) L. Ackermann, R. Jeyachandran, H. K. Potukuchi, P. Novák, L. Büttner, "Palladium-Catalyzed Dehydrogenative Direct Arylations of 1,2,3-Triazoles" Org. Lett. 2010, 12, 2056-2059. Abstract>

71) L. Ackermann, "Transition Metal-Catalyzed Direct Arylations via C-H Bond Cleavages" Pure Appl. Chem. 2010, 82, 1403-1413. Abstract>

70) L. Ackermann, H. K. Potukuchi, A. R. Kapdi, C. Schulzke, "Kumada-Corriu Cross-Couplings with 2-Pyridyl Grignard Reagents" Chem. Eur. J. 2010, 16, 3300-3303. Abstract>

69) L. Ackermann, H. K. Potukuchi, A. Althammer, R. Born, P. Mayer, "Tetra-ortho-Substituted Biaryls through Palladium-Catalyzed Suzuki-Miyaura Couplings with a Diaminochlorophosphine Ligand" Org. Lett. 2010, 12, 1004-1007. Abstract>

68) L. Ackermann, S. Barfüßer, J. Pospech, "Palladium-Catalyzed Direct Arylations, Alkenylations, and Benzylations through C-H Bond Cleavages with Sulfamates or Phosphates as Electrophiles" Org. Lett. 2010, 12, 724-726.Abstract> (highlighted in Synfacts 2010, 694)

67) L. Ackermann, C. Wechsler, A. R. Kapdi, A. Althammer, "Air-Stable Diaminophosphine Sulfides as Preligands for Nickel-Catalyzed Cross-Couplings of Unactivated Fluoro(hetero)arenes" Synlett 2010, 294-298.Abstract>


2009


66) L. Ackermann, R. Vicente, A. Kapdi, "Transition-Metal-Catalyzed Direct Arylations of (Hetero)Arenes via C-H Bond Cleavage" Angew. Chem. 2009, 121, 9976-10011; Angew. Chem. Int. Ed. 2009, 48, 9792-9826. Abstract>

65) L. Ackermann, P. Novák, "Regioselective Ruthenium-Catalyzed Direct Benzylations of Arenes through C-H Bond Cleavages" Org. Lett. 2009, 11, 4966-4969. Abstract>

64) L. Ackermann, R. Vicente, "Catalytic Direct Arylations in Polyethylene Glycol (PEG): Recyclable Palladium(0) Catalyst for C-H Bond Cleavages in the Presence of Air" Org. Lett. 2009, 11, 4922-4925. Abstract> (highlighted in Synfacts 2010, 362; highlighted in Organic Chemistry Portal)

63) L. Ackermann, R. Vicente, N. Hofmann, "Air-Stable Secondary Phosphine Oxide as Preligand for Palladium-Catalyzed Intramolecular α-Arylations with Chloroarenes" Org. Lett. 2009, 11, 4274-4276. Abstract> highlighted in Organic Chemistry Portal)

62) L. Ackermann, H. K. Potukuchi, "Palladium-Catalyzed Cross-Coupling Reactions of 2-Pyridylborates with Air-Stable HASPO Preligands" Synlett 2009, 2852-2856. Abstract>

61) L. Ackermann, P. Novák, R. Vicente, N. Hofmann, "Ruthenium-Catalyzed Regioselective Direct Alkylation of Arenes with Unactivated Alkyl Halides through C-H Bond Cleavage" Angew. Chem. 2009, 121, 6161-6164; Angew. Chem. Int. Ed. 2009, 48, 6045-6048. Abstract> (Selected as hot paper)

60) L. Ackermann, A. Althammer, Peter Mayer, "Palladium-Catalyzed Direct Arylation-Based Domino Synthesis of Annulated N-Heterocycles Using Alkenyl or (Hetero)Aryl 1,2-Dihalides" Synthesis 2009, 3493-3503.Abstract> highlighted in Organic Chemistry Portal)

59) L. Ackermann, R. Sandmann, M. Schinkel, M. V. Kondrashov, "Palladium-Catalyzed Sequential Indole Synthesis Using Sterically Hindered Amines" Tetrahderon (Symposia in print) 2009, 65, 8930-8939. Abstract>

58) L. Ackermann, S. Barfüßer, H. K. Potukuchi, "Copper-Catalyzed N-Arylation/Hydroamin(d)ation Domino Synthesis of Indoles and its Application to the Preparation of a Chek1/KDR Kinase Inhibitor Pharmacophore" Adv. Synth. Catal. 2009, 351, 1064-1072.Abstract> (highlighted in Synfacts 2009, 836)

57) L. Ackermann, S. Barfüßer, H. K. Potukuchi, "Copper-Catalyzed N-Arylation/Hydroamin(d)ation Domino Synthesis of Indoles and its Application to the Preparation of a Chek1/KDR Kinase Inhibitor Pharmacophore" Adv. Synth. Catal. 2009, 351, 1064-1072.Abstract>

56) L. Ackermann, R. Sandmann, L. T. Kaspar, "Two Titanium-Catalyzed Reaction Sequences for Syntheses of Pyrroles from (E/Z)-Chloroenynes or α-Haloalkynols" Org. Lett. 2009, 11, 2031-2034.Abstract> (highlighted in Synfacts 2009, 718)

55) L. Ackermann, R. Sandmann, M. V. Kondrashov, "Thieme chemistry journal awardees - where are they now? Palladium-Catalyzed N-Arylation/Hydroamination Sequence for the Synthesis of Indoles with Sterically Demanding N-Substiuents" Synlett 2009, 1219-1222.Abstract>

54) L. Ackermann, R. Born, R. Vicente, "Ruthenium-Catalyzed Direct Arylations of N-Aryl 1,2,3-Triazoles with Aryl Chlorides as Electrophiles" ChemSusChem 2009, 546-549.Abstract>

53) L. Ackermann, A. Althammer, S. Fenner, "Palladium-Catalyzed Direct Arylations of Heteroarenes with Tosylates and Mesylates" Angew. Chem. 2009, 121, 207-210; Angew. Chem. Int. Ed. 2009, 48, 201-204. Abstract> (Selected as hot paper) (Highlighted in Synfacts 2009, 260)

52) L. Ackermann, A. Althammer, "Moderne Magnesiumorganische Chemie. Neues von der Grignard-Reaktion", Chem. Unserer Zeit 2009, 43, 74-83.Abstract>

51) L. Ackermann, S. Barfüßer, "Palladium-Catalyzed Direct C-3 Arylations of Indoles with an Air-Stable HASPO" Synlett 2009, 808-812.Abstract>

50) L. Ackermann, R. Vicente, "Sustainable Ruthenium-Catalyzed Direct Arylations through C-H Bond Functionalizations", in Experiments in Green and Sustainable Chemistry (Eds.: H. W. Roesky, D. Kennepohl), Wiley-VCH, Weinheim, 2009, 64-69.

49) L. Ackermann, R. Born, "Mizoroki-Heck Reactions with Metals other than Palladium", in The Mizoroki-Heck Reaction (Ed.: M. Oestreich), Wiley, Chichester, 2009, 383-403.

48) L. Ackermann, R. Vicente, "Metal-Catalyzed Direct Arylations", in Modern Arylation Methods (Ed.: L. Ackermann), Wiley-VCH, Weinheim, 2009, 311-333.

47) L. Ackermann, "Arylation Reactions: A Historical Perspective", in Modern Arylation Methods (Ed.: L. Ackermann), Wiley-VCH, Weinheim, 2009, 1-24.

46) L. Ackermann (Ed.), "Modern Arylation Methods", Wiley-VCH, Weinheim, January 2009, 543 pages. ISBN: 978-3-527-31937-4.


2008


45) L. Ackermann, M. Mulzer, "Dehydrative Direct Arylations of Arenes with Phenols via Ruthenium-Catalyzed C-H and C-OH Bond Functionalizations" Org. Lett. 2008, 10, 5043-5045.Abstract>

44) S. I. Kozhushkov, D. S. Yufit, L. Ackermann, "Ruthenium-Catalyzed Hydroarylations of Methylenecyclopropanes: Mild C-H Bond Functionalizations with Conservation of Cyclopropane Rings" Org. Lett. 2008, 10, 3409-3412. Abstract>

43) L. Ackermann, H. K. Potukuchi, D. Landsberg, R. Vicente, "Copper-Catalyzed "Click" Reaction/Direct Arylation Sequence: Modular Syntheses of 1,2,3-Triazoles" Org. Lett. 2008, 10, 3081-3084. Abstract> highlighted in Organic Chemistry Portal) (among the most cited publications in 2008-2010)

42) L. Ackermann, R. Vicente, A. Althammer, "Assisted Ruthenium-Catalyzed C-H Bond Activation: Carboxylic Acids as Cocatalysts for Generally Applicable Direct Arylations in Apolar Solvents" Org. Lett. 2008, 10, 2299-2302. Abstract> (the most cited publication in 2008-2010)

41) L. Ackermann, A. Althammer, R. Born, "[RuCl3(H2O)n]-catalyzed direct arylations" Tetrahedron (Symposia in print) 2008, 64, 6115-6124.Abstract>

40) L. Ackermann, "Chiral Secondary Phosphine Oxides as Preligands", in Trivalent Phosphorus Compounds in Asymmetric Catalysis, Synthesis and Applications Ed.: A. Börner), Wiley-VCH, Weinheim, 2008, 831-847.

39) L. Ackermann, A. Althammer "Phosphoric Acid Diesters as Efficient Catalysts for Hydroaminations of Nonactivated Alkenes and an Application to Asymmetric Hydroaminations", Synlett 2008, 995-998. Abstract> (highlighted in Synfacts 2008, 639)

38) L. Ackermann, R. Vicente, R. Born, "Palladium-Catalyzed Direct Arylations of 1,2,3-Triazoles with Aryl Chlorides Using Conventional Heating" Adv. Synth. Catal. 2008, 350, 741-748. Abstract> (the most cited publication in 2007-2008)

37) L. Ackermann, R. Sandmann, A. Villar, L. T. Kaspar, "Annulation of internal alkynes through a hydroamination/aza-Heck reaction sequence for the regioselective synthesis of indoles" Tetrahedron (Symposia in print) 2008, 64, 769-777. Abstract> (Highlighted in Synfacts 2008, 355)


2007


36) L. Ackermann, "Chelation-Assisted Arylation via C-H Bond Cleavage", in Top. Organomet. Chem. 2007, 24, 35-60. Abstract>

35) L. Ackermann, A. Althammer, R. Born, "[RuCl3(H2O)n]-Catalyzed Direct Arylations with Bromides as Electrophiles" Synlett 2007, 2833-2836. Abstract>

34) L. Ackermann, R. Born, P. Álvarez-Bercedo, "Ruthenium(IV) Alkylidenes as Precatalysts for Direct Arylations of Alkenes with Aryl Chlorides and an Application to Sequential Catalysis" Angew. Chem. 2007, 119, 6482-6485; Angew. Chem. Int. Ed. 2007, 46, 6364-6367.Abstract> (Selected as hot paper)

33) L. Ackermann, L. T. Kaspar, "TiCl4-Catalyzed Indirect Anti-Markovnikov Hydration of Alkynes: Application to the Synthesis of Benzo[b]furans" J. Org. Chem. 2007, 72, 6149-6153.Abstract> highlighted in Organic Chemistry Portal)

32) L. Ackermann, L. T. Kaspar, A. Althammer, "Hydroaminations of Unactivated Alkenes with Basic Alkylamines: Group 4 Metal Halide Catalysts and Bronsted-Acid Organocatalysts" Org. Biomol. Chem. 2007, 5, 1975-1978. Abstract>

31) L. Ackermann, A. Althammer "Domino NH/CH Bond Activation: Palladium-Catalyzed Synthesis of Annulated Heterocycles Using Dichloro(hetero)arenes" Angew. Chem. 2007, 119, 1652-1654; Angew. Chem. Int. Ed. 2007, 46, 1627-1629. Abstract> (Selected as hot paper)

30) L. Ackermann, "Catalytic Arylations with Challenging Substrates: From Air-Stable HASPO Preligands to Indole Syntheses and C-H-Bond Functionalizations" Synlett 2007, 507-526. Abstract>


2006


29) L. Ackermann, J. H. Spatz, C. J. Gschrei, R. Born, A. Althammer, "A Diaminochlorophosphine for Palladium-Catalyzed Arylations of Amines and Ketones" Angew. Chem. 2006, 118, 7789-7792; Angew. Chem. Int. Ed. 2006, 45, 7627-7630. Abstract>

28) L. Ackermann, A. Althammer, "Air-Stable PinP(O)H as Preligand for Palladium-Catalyzed Kumada Couplings of Unactivated Tosylates" Org. Lett. 2006, 8, 3457-3460. Abstract> highlighted in Organic Chemistry Portal)

27) L. Ackermann, A. Althammer, "One-pot indole synthesis consisting of a ruthenium-catalyzed hydroamination and a palladium-catalyzed Heck reaction using 2-chloroaniline" Synlett 2006, 3125-3129. Abstract>

26) L. Ackermann, C. J. Gschrei, A. Althammer, M. Riederer, "Cross-coupling reactions of aryl and vinyl chlorides catalyzed by a palladium complex derived from an air-stable H-phosphonate" Chem. Commun. 2006, 1419-1421. Abstract>

25) L. Ackermann, "Air- and Moisture-Stable Secondary Phosphine Oxides as Preligands in Catalysis" Synthesis 2006, 1557-1571. Abstract>

24) L. Ackermann, A. Althammer, R. Born, "Catalytic Arylation Reactions by C-H Bond Activation with Aryl Tosylates" Angew. Chem. 2006, 118, 2681-2685; Angew. Chem. Int. Ed. 2006, 45, 2619-2622. Abstract>

23) L. Ackermann, R. Born, J. H. Spatz, A. Althammer, C. J. Gschrei "Air-Stable Phosphine Oxides as Preligands for Catalytic Activation Reactions of C-Cl-, C-F- and C-H-Bonds" Pure Appl. Chem. 2006, 78, 209-214.Abstract>


2005


22) L. Ackermann, R. Born, J. H. Spatz, D. Meyer, "Efficient Aryl-(Hetero)Aryl Coupling via Activation of C-Cl and C-F Bonds Using Nickel Complexes of Air-Stable Phosphine Oxides" Angew. Chem. 2005, 117,7382-7386; Angew. Chem. Int. Ed. 2005, 44, 7216-7219.Abstract> (Selected as hot paper)

21) L. T. Kaspar, L. Ackermann, "Three-component indole synthesis using ortho-dihaloarenes" Tetrahedron (Symposia in print) 2005, 61, 11311-11316. Abstract> highlighted in Organic Chemistry Portal)

20) L. T. Kaspar, B. Fingerhut, L. Ackermann, "Titanium-Catalyzed Intermolecular Hydroamination of Vinylarenes" Angew. Chem. 2005, 117, 6126-6128; Angew. Chem. Int. Ed. 2005, 44, 5972-5974. Abstract>

19) L. Ackermann, "Phosphine Oxides as Preligands in Ruthenium-Catalyzed Arylations via C-H-Bond Functionalization Using Aryl Chlorides" Org. Lett. 2005, 7, 3123-3125. Abstract>

18) L. Ackermann, R. Born, "Modular Diamino and Dioxophosphine Oxides and Chlorides as Ligands for Transition-Metal-Catalyzed C-C and C-N Bond Formations Using Aryl Chlorides" Angew. Chem. 2005, 117, 2497-2500; Angew. Chem. Int. Ed. 2005, 44, 2444-2447. Abstract>

17) L. Ackermann, "General and Efficient Indole Syntheses Based on Catalytic Amination Reactions", Org. Lett. 2005, 7, 439-442. Abstract>


2004


16) L. Ackermann, L. T. Kaspar, C. J. Gschrei, "Hydroamination/Heck reaction sequence for a highly regioselective one-pot synthesis of indoles using 2-chloroaniline", Chem. Commun. 2004, 2824-2825. Abstract>

15) L. Ackermann, R. Born, "TiCl4/t-BuNH2 as the sole catalyst for a hydro­amination-based Fischer indole synthesis", Tetrahderon Lett. 2004, 45, 9541-9544. Abstract>

14) L. Ackermann, L. T. Kaspar, C. J. Gschrei "TiCl4-Catalyzed Intermolecular Hydroamination Reactions of Norbornene", Org. Lett. 2004, 6, 2515-2518. Abstract>


2003


13) L. Ackermann, "TiCl4-catalyzed Intermolecular Hydroamination Reactions", Organometallics 2003, 22, 4367-4368. Abstract>

12) L. Ackermann, R. G. Bergman, R. N. Loy, "Use of Group 4 Bis(sulfonamido) Complexes in the Intramolecular Hydroamination of Alkynes and Allenes", J. Am. Chem. Soc. 2003, 125, 11956-11963. Abstract>


2002


11) L. Ackermann, R. G. Bergman, "A Highly Reactive Titanium Precatalyst for Intramolecular Hydroamination Reactions", Org. Lett. 2002, 4, 1475-1478. Abstract>


2001


10) A. Fürstner, H. Krause, L. Ackermann, C. W. Lehmann, "N-Heterocyclic carbenes can coexist with alkenes and C-H acidic sites", Chem. Commun. 2001, 2240-2241. Abstract>

9) A. Fürstner, L. Ackermann, B. Gabor, R. Goddard, C. W. Lehmann, R. Mynott, F. Stelzer, O. R. Thiel, "Comparative Investigation of Ruthenium-Based Metathesis Catalysts Bearing N-Heterocyclic Carbene (NHC) Ligands", Chem. Eur. J. 2001, 7, 3236-3253. Abstract>

8) A. Fürstner, L. Ackermann, K. N. Beck, H. Hori, D. Koch, K. Langemann, M. Liebl, C. Six, W. Leitner, "Olefin Metathesis in Supercritical Carbon Dioxide", J. Am. Chem. Soc. 2001, 123, 9000-9006. Abstract>

7) L. Ackermann, C. Bruneau, P. H. Dixneuf, "Simple New Three-component Catalytic System for Enyne Metathesis ", Synlett 2001, 397-399. Abstract>

6) A. Fürstner, O. R. Thiel, L. Ackermann, "Exploiting the Reversibility of Olefin Metathesis. Synthesis of Macrocyclic Trisubstituted Alkenes and (R,R)-(-)-Pyrenophorin", Org. Lett. 2001, 3, 449-451. Abstract>


2000


5) L. Ackermann, D. El Tom, A. Fürstner, "Ruthenium Carbene Complexes with Imidazol-2-ylidene Ligands: Syntheses of Conduritol Derivatives Reveals Superior RCM Activity", Tetrahderon 2000, 56, 2195-2202. Abstract>

4) A. Fürstner, O. R. Thiel, L. Ackermann, H.-J. Schanz, S. P. Nolan, "Ruthenium Carbene Complexes with N,N'-Bis(mesityl)imidazol-2-ylidene Ligands: RCM Catalysts of Extended Scope", J. Org. Chem. 2000, 65, 2204-2207. Abstract>


1999


3) L. Ackermann, A. Fürstner, T. Weskamp, F. J. Kohl, W. A. Herrmann, "Ruthenium carbene complexes with imidazolin-2-ylidene ligands allow the formation of tetrasubstituted cycloalkenes by ring-closing metathesis (RCM)", Tetrahedron Lett. 1999, 40, 4787-4790. Abstract>

2) A. Fürstner, L. Ackermann, "A most user-friendly protocol for ring-closing metathesis reactions", Chem. Commun. 1999, 95-96. Abstract>

1) L. Ackermann, A. Heidbreder, F. Wurche, F.-G. Klärner, J. Mattay, "Mechanistic Studies on PET-oxidative cyclization of unsaturated silyl enol ethers: dependence of the regioselectivity on alcohol addition and pressure effects", Perkin Trans. 2 1999, 863-869. Abstract>


Additional Publications


L. Ackermann, Angew. Chem. Int. Ed. 2010, 49, 3716. (author profile)
A. Althammer, L. Ackermann, "Hochschule trifft Industrie" Nachr. Chem. 2008, 56, 71.
L. Ackermann, "The Claisen Rearrangement. Methods and Applications" Nachr. Chem. 2007, 55, 899.
L. Ackermann, "Bürgenstock 2005" Nachr. Chem. 2005, 53, 817.


L. Ackermann, "Development of Air-Stable Heteroatom-Substituted Secondary Phosphine Oxides (HASPO) as Preligands for Catalytic Coupling Reactions" - Habilitation, München 2007.
L. Ackermann, "Entwicklung und Anwendung neuartiger Präkatalysatoren für die Olefinmetathese" - Dissertation, Der Andere Verlag 2001, ISBN: 3935316585.