Difunctionalization of bicyclo[1.1.0]butanes enabled by merging C−C cleavage and ruthenium-catalysed remote C−H activation S. Chen, Z. Xu, B. Yuan, X.-Y. Gou, L. Ackermann
Nat. Synth 2025, in press
Abstract

Enantioselective C–H annulations enabled by either nickel- or cobalt-electrocatalysed C–H activation for catalyst-controlled chemodivergence T. von Münchow,^§ N. K. Pandit,^§ S. Dana, P. Boos, S. E. Peters, J. Boucat, Y.-R. Liu, A. Scheremetjew, L. Ackermann
Nat. Catal 2025, 8, 257–269
Abstract

Ruthenaphoto-catalyzed ortho-C–H alkylation with secondary alkyl halides: SET-enabled ruthenium(II/III/IV) manifold Y. Wang,^§ B. Yuan,^§ X. Chang,^§ L. Ackermann
Chem 2025, 11, 102387
Abstract

Machine learning-guided yield optimization for palladaelectro-catalyzed annulation reaction X. Hou, S. Li, J. Frey, X. Hong, L. Ackermann
Chem 2024, 10, 2283-2294
Abstract

Iron-catalyzed stereoselective C–H alkylation for simultaneous construction of C–N axial and C-central chirality Z-J. Zhang, N. Jacob, S. Bhatia, P. Boos, X. Chen, J. C. DeMuth, A. M. Messinis, B. B. Jei, J. C. A. Oliveira, A. Radović, M. L. Neidig, J. Wencel-Delord, L Ackermann
Nat. Commun 2024, 15, 3503
Abstract

Room temperature photo-promoted iron-catalysed arene C–H alkenylation without Grignard reagents A. M. Messinis, T. von Münchow, M. Surke, L. Ackermann
Nat. Catal 2024, 7, 273–284
Abstract

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification Z. Lin,^§ U. Dhawa,^§ X. Hou,^§ M. Surke, B. Yuan, S.-W. Li, Y.-C. Liou, M. J. Johansson, L.-C. Xu, C.-H. Chao, X. Hong, L. Ackermann
Nat. Commun 2023, 14, 4224
Abstract

Data-driven design of new chiral carboxylic acid for construction of indoles with C-central and C–N axial chirality via cobalt catalysis Z-J. Zhang, S.-W. L, J. C. A. Oliveira, Y. Li, X. Chen, S.-Q. Zhang, L.-C. Xu, T. Rogge, X. Hong, L. Ackermann
Nat. Commun 2023, 14, 3149
Abstract

Enantioselectivity prediction of pallada-electrocatalysed C–H activation using transition state knowledge in machine learning L.-C. Xu, J. Frey, X. Hou, S.-Q. Zhang, Y.-Y. Li, J. C. A. Oliveira, S.-W. Li, L. Ackermann, X. Hong
Nat. Synth 2023, 2, 321–330
Abstract

Enantioselective electrochemical cobalt-catalyzed aryl C–H activation reactions T. von Münchow^§, S. Dana^§, Y. Xu, B. Yuan, L. Ackermann
Science 2023, 379, 1036–1042
Abstract

Rhodaelectro-catalyzed access to chromones via formyl C–H activation towards peptide electro-labeling M. Stangier, A. Messinis, J. C. A. Oliveira, H. Yu, L. Ackermann
Nat. Commun 2021, 12, 4736
Abstract

Late-stage C–H functionalization offers new opportunities in drug discovery L. Guillemard, N. Kaplaneris, L. Ackermann, M. Johansson
Nat. Rev. Chem 2021, 5, 522–545
Abstract

C–H activation T. Rogge, N. Kaplaneris, N. Chatani, J. Kim, S. Chang, B. Punji, L. L. Schafer, D. G. Musaev, J. Wencel-Delord, C. A. Roberts, R. Sarpong, Z. E. Wilson, M. A. Brimble, M. J. Johansson, L. Ackermann
Nat. Rev. Methods Primers 2021, 1, 43
Abstract

Electrocatalytic C–H phosphorylation through nickel(III/IV/II) catalysis S.-K. Zhang, A. Del Vecchio, R. Kuniyil, A. M. Messinis, Z. Lin, L. Ackermann
Chem 2021, 7, 1379-1392
Abstract

Cobalt-catalysed C–H methylation for late-stage drug diversification S. D. Friis, M. J. Johansson, L. Ackermann
Nat. Chem 2020, 12
Abstract

Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes N. Kaplaneris, J. Son, L. Mendive-Tapia, A. Kopp, N. D. Barth, I. Maksso, M. Vendrell, L. Ackermann
Nat. Commun 2021, 11, 3389
Abstract